At Interphex 2021 in New York, Syntegon (formerly Bosch Packaging Technology) presents new lab-scale and small-batch filling solutions for solid and liquid pharmaceuticals. “The need for smaller quantities of highly potent drugs is rising continuously. We have put these solutions in the focus of our current development activities and are proud to offer our customers a number of exciting new technologies”, says Thomas Mauritzen, general manager at Syntegon Minneapolis.
Both the new GKF 60 capsule filling machine and the Versynta Flexible Filling Platform (FFP) make their first live appearance at booth 3139 from 19-21 October, 2021. They are complemented by a comprehensive portfolio of services and new digital solutions.
GKF 60 — Syntegon’s new standards in capsule filling
The new GKF 60 capsule filling machine enables the development of new formulations with a wide variety of dosing systems at different OEB levels and with an optional 100 percent gravimetric weighing system. The mobile machine with only six stations requires little space and few format parts. Standard dosing modules for DPI, pellets, tablets, or liquids, as well as the mini-bowl station for scale-up to the next larger production machine, offer the highest flexibility.
Moreover, the newly developed piezo dosing station can accurately fill very small quantities starting at 0.1 milligram filling weight. Customers can choose between a standard, containment, and a combi solution. The latter can be adapted for both simple and highly potent formulations up to OEB5 high-containment in just a few steps.
Versynta FFP — Modular small-batch solution for liquid pharmaceuticals
Another innovation, which was developed for highly potent pharmaceuticals, is Syntegon’s Versynta FFP. The modular and individually configurable small-batch solution with an integrated isolator for liquid pharmaceuticals achieves precise product yields at low output.
The platform is based on pre-developed and tested modules that can be flexibly combined. It handles different container types such as vials, syringes, and cartridges and can be converted to other filling systems, including single-use solutions. The Pharma Handling Unit, a four-axis robot developed by Syntegon, allows for safe and gentle transport without glass-to-glass contact. Versynta FFP processes up to 3,600 containers per hour and comes with 100 percent in-process control.
Pharmaceutical competence from formulation to filling
Visitors to booth 3139 have the opportunity to discuss their current and future projects with the Syntegon experts. Syntegon’s portfolio ranges from single machines to complete solutions for lab-scale to high-speed applications. They include sterilization, freeze-drying, filling, closing, inspection equipment for liquid pharmaceuticals, and assembly solutions for medical and diagnostic devices.
The portfolio further covers all process steps for solid dosage forms, such as tablet pressing and coating, capsule filling, and continuous manufacturing solutions. Moreover, Syntegon can rely on 40 years of isolator competence in the U.S.: “We developed barrier systems before they were in fashion,” Thomas Mauritzen says. A new campaign further underlines this fact.
Tailored services and digital solutions to meet customers’ needs
The portfolio is completed by comprehensive consulting and service offerings along the entire machine lifecycle. Syntegon’s customized offerings range from spare parts and field service to stock optimization, modernization, and preventive maintenance, as well as remote and data-based services.
As of November, all Syntegon machines will be delivered ‘IoT ready’ and provide interfaces for numerous digital solutions. Customers benefit from a holistic concept for generating, processing, and analyzing machine data, entering a new level of digitalization.