Credence MedSystems
Companion Safety Syringe System. The Companion allows pharmaceutical manufacturers to provide critical usability and safety features to their end-users while integrating with existing syringe barrels and primary packaging components. Photo - Credence MedSystems

The US-headquartered Credence MedSystems and German-based Schott have formed a collaboration to apply Credence Companion technology with Schott’s pre-fillable syriQ glass and Schott Toppac polymer syringe systems. The two companies will work together to integrate the technologies and provide the pharmaceutical industry with an innovative and differentiated offering to deliver injectable medications via prefilled syringes.

Pharmaceutical manufacturers are driven to provide their end-users with drug delivery systems encompassing enhanced usability and safety features that facilitate administering their medications, protect from accidental needlesticks, and adhere to international needlestick regulations. They look for these systems to be compatible with the variety of available syringe barrel options that meet varied needs across multiple drug products and use environment requirements.

Credence MedSystems, an innovator in injectable drug delivery technology, has developed the Companion Safety Syringe System. The Companion allows pharmaceutical manufacturers to provide critical usability and safety features to their end-users while integrating with existing syringe barrels and primary packaging components. At the injection completion, the user receives an end-of-dose cue in the form of a ‘click,’ indicating that the full dose has been delivered, as the needle automatically retracts into the syringe barrel, thereby protecting the user and preventing reuse. In addition to the safety and usability benefits for the end-user, the robust design enables reliable functionality and avoids unintentional activation before the end of the injection.

According to the company, to facilitate implementation for pharmaceutical manufacturers and offer this technology for various applications and therapeutic fields, a fully integrated solution that is compatible with various syringe barrels is a prerequisite. The integrated approach to safety, where no additional devices need to be assembled after syringe filling, brings operational efficiencies to drug manufacturers. This is where the value of the partnership between Credence and Schott Is said to be beneficial.

By designing solutions in primary pharmaceutical packaging, Schott ensures that medicines are safe and easy to use for people around the world. For human health and the various requirements for 7bn individuals, Schott has established a full proven and established portfolio of syriQ glass syringes and Schott Toppac polymer pre-fillable syringes as well as various related packaging components.

Bringing together the established Companion technology and the existing syringes from Schott, this partnership targets a pre-validated and pre-assembled portfolio of passive integrated needle systems with various available syringe sizes made of both glass and high-quality Cyclic Olefin Copolymer materials. With this, pharmaceutical companies will be given full flexibility in choosing the right barrel that fits each application’s requirements, with the safety system integrated.

“Integrating our established Companion technology with a broad variety of existing syringe barrels from Schott is an important milestone in offering innovation without change to the pharmaceutical industry,” states John Merhige, Credence’s chief commercial officer. “This allows pharma the confidence to work with already validated systems but the freedom to choose the perfect fit from a wide portfolio.”

Fabian Stöcker, vice president Global Strategy & Innovation at Schott Pharmaceutical Systems, added, “Having over 20 years of experience in the field of syringes, we are happy that, with this partnership and product offering, we can even go a step further to create a new, synergistic and trusted offering for glass and polymer syringe systems that is responsive to the growing needs of the industry. To our knowledge, we will provide the first integrated needle safety system on the market with a polymer pre-fillable syringe by integrating the Credence Companion technology into our Schott Toppac syringes.”

Schott and Credence are currently defining implementation timelines and product offerings in advance of communication with their pharmaceutical customers.

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