Berry Healthcare’s Vistop PP36 patented tamper-evident closure

Following the International Sustainability and Carbon Certificate (ISCC) Plus accreditation of its Berry Astra Plastique facility in Saint-Georges-de-Reneins, France, Berry Healthcare’s Vistop PP36 patented tamper-evident closure for autoclave sterilization can now be specified incorporating advanced recycling resin in both circular PP and PE. This meets customer demands for more sustainable packaging while maintaining the closure’s high standards of product protection and user safety.

Ideal for medical applications and hospital operating theatres, the versatility of the patented Vistop PP36 – said to be the first on the market to feature a tamper-evident ring – has been proven through over 40 years of safe and reliable performance for a variety of applications for the leading pharmaceutical and healthcare companies. Today, with commercialized approval in over 70 countries, it offers accelerated speed to market to effectively support manufacturers’ new product development programs.

This is of particular importance currently, with Berry Healthcare experiencing increased demand for sterilizable tamper-evident closure as manufacturing companies seek effective anti-theft medical packaging solutions to help counter the growing problem of falsified medicines and sterilization failures.

The Vistop PP36 ensures ease of opening without the need for extra pressure or force and provides a clear visual sign of tamper evidence, with the tamper-evident ring breaking completely after initial unscrewing. The design of the closure delivers the tightness required for a perfect fit and effective product security, and the flexible inner seal adapts easily to different shapes, tolerances, and applications of pressure.

The Vistop PP36 sterilizable range and applications include:

  • 1684 One port perfusion cap with chlorobutyl liner and aluminium foil used for parenteral IV administration
  • 1482 Irrigation cap with PP Plug used for disinfection in operating rooms and hospital settings
  • 1866 Irrigation cap with chlorobutyl liner for PP or glass bottle

The tamper-evident ring improves stability on filling lines and highly profiled grooves in the outer shell provide an excellent contact surface for the placement of caps onto bottles by automated fitting machines, while at the same time offering comfortable handling for end users.

The Vistop PP36 is manufactured in a class 10,000 clean room at Berry Healthcare’s ISO 15378 accredited Berry Astra Plastique facility. The closure meets several international requirements and approvals, including FDA and AMM, and conforms with the European and the United States pharmacopoeia.

“The availability of recycled resin for our Vistop PP36 further increases the appeal of the closure, combining with the existing benefits of safeguarding product integrity and ensuring ease of administration that improve patient safety and enhance the overall patient experience,” comments Franck Cordier South Europe Operations director of Berry Healthcare. “Consumers are increasingly seeking sustainable solutions in all areas of their lives, and the sustainability credentials of the closure will help to further enhance a company’s reputation and standing in the healthcare market.”

For further information on Berry Healthcare’s range of solutions, visit

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